Foxp3+ regulatory T cells: selfishness under scrutiny.

@article{Stephens2007Foxp3RT,
  title={Foxp3+ regulatory T cells: selfishness under scrutiny.},
  author={Geoffrey L. Stephens and Ethan M Shevach},
  journal={Immunity},
  year={2007},
  volume={27 3},
  pages={417-9}
}
The Foxp3+ T cell lineage is thought to arise from self-specific precursors during development. By using a unique mouse model, Pacholczyk et al. (2007) present compelling evidence that self-specific cells are exceedingly rare among Foxp3(-) and, surprisingly, Foxp3+ subsets. 

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