Foxo1-mediated inflammatory response after cerebral hemorrhage in rats.

  title={Foxo1-mediated inflammatory response after cerebral hemorrhage in rats.},
  author={Zhenyu Li and Qi He and Xuan Zhai and Y. -M. You and Lingyu Li and Yanghao Hou and Faming He and Yong Zhao and Jing Zhao},
  journal={Neuroscience letters},
The forkhead box O (Foxo) family of transcription factors plays a crucial role in cell apoptosis, immune regulation, and tissue development. Foxo1, as the foremost member of the Foxo family, regulates a wide range of molecular signals in many tissues, including tumor, liver, and brain. This study investigated Foxo1 expression at different time points and in different brain areas, and the role of Foxo1 in vivo in regulating inflammatory injury in a rat model of autologous blood-injected cerebral… CONTINUE READING
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