FoxM1 regulates Sirt1 expression in glioma cells.

  title={FoxM1 regulates Sirt1 expression in glioma cells.},
  author={G Y Zhu and B-Z Shi and Y Li},
  journal={European review for medical and pharmacological sciences},
  volume={18 2},
  • G Y Zhu, B-Z Shi, Y Li
  • Published 2014 in
    European review for medical and pharmacological…
BACKGROUND AND OBJECTIVES Glioma accounts for most of primary malignant brain tumors and usually results in poor survival. However, the key signaling networks regulating glioma cell proliferation remain poorly defined. The forkhead box M1 (FoxM1) is a key transcription factor regulating multiple aspects of cell biology. Prior studies have shown that FoxM1 is overexpressed in glioma and plays a critical role in cancer development and progression. MATERIALS AND METHODS Western blot and Real… CONTINUE READING


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