Fowlpox virus encodes two p28-like ubiquitin ligases that are expressed early and late during infection.

Abstract

Many cellular processes are regulated by the ubiquitin-proteasome system. Therefore, it is not surprising that viruses have adapted ways to manipulate the ubiquitin-proteasome system to their own advantage. p28 is a poxvirus encoded ubiquitin ligase that contains an N-terminal KilA-N DNA binding domain and a C-terminal RING domain required for ubiquitin… (More)
DOI: 10.1016/j.virol.2014.05.018

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