Fourteen‐day Toxicity Study of 1,3,5‐Trinitrobenzene in Fischer 344 Rats

@article{Reddy1996FourteendayTS,
  title={Fourteen‐day Toxicity Study of 1,3,5‐Trinitrobenzene in Fischer 344 Rats},
  author={T. Reddy and G. Olson and B. Wiechman and G. Reddy and M. Robinson and J. Torsella and F. Daniel},
  journal={Journal of Applied Toxicology},
  year={1996},
  volume={16}
}
Toxic effects of 1,3,5‐trinitrobenzene (TNB) in male and female rats were evaluated by feeding powdered certified laboratory chow diet supplemented with varied concentrations of TNB (0, 50, 200, 400, 800 and 1200 mg kg−1 diet) for 14 days. Food intake by female rats in 400, 800 and 1200 mg TNB diet groups was reduced and resulted in a significant decrease in absolute body weights (BW). Food and water consumption by male rats in high‐dose groups (800 and 1200 mg TNB kg−1 diet) was also reduced… Expand
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