Fournier's gangrene: review of 120 patients and predictors of mortality.

@article{Ylmazlar2014FourniersGR,
  title={Fournier's gangrene: review of 120 patients and predictors of mortality.},
  author={Tuncay Yılmazlar and {\"O}zgen Işık and Ersin {\"O}zt{\"u}rk and Ali {\"O}zer and Barış G{\"u}lc{\"u} and Ilker Ercan},
  journal={Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma \& emergency surgery : TJTES},
  year={2014},
  volume={20 5},
  pages={
          333-7
        }
}
  • T. Yılmazlar, Ö. Işık, +3 authors I. Ercan
  • Published 1 September 2014
  • Medicine
  • Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
BACKGROUND Fournier's gangrene (FG) is a devastating and potentially fatal disease requiring prompt and aggressive debridement. In this study, it was aimed to assess the predictors of mortality in a large cohort. METHODS Prospectively maintained data of patients with FG were analyzed. Demographic data, duration of symptoms, Uludag Fournier's Gangrene Severity Index (UFGSI) scores, co-morbidities [particularly diabetes mellitus (DM)], etiologies, number of debridement, stoma requirements… 
Fournier's gangrene: a modern analysis of predictors of outcomes.
TLDR
Multivariate analysis showed FGSI score correlates with more surgical intervention, longer hospitalization, sepsis, complication and mortality within this patient population.
Gender does not affect the prognosis of Fournier's gangrene: a case-matched study.
TLDR
FG is often more extensive in females and seems to be associated with anatomical features of female pelvis, however, female gender is not a factor affecting prognosis of patients with FG.
Fournier's gangrene: A retrospective analysis of 25 patients.
  • Metin Yücel, Adnan Özpek, +5 authors G. Bas
  • Medicine
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
  • 2017
TLDR
In Fournier's gangrene, early diagnosis, effective resuscitation, aggressive debridement, and VAC application in suitable cases may reduce the morbidity and mortality rates and the need for an ostomy.
Comparison of Mortality in Fournier's Gangrene with the Two Scoring Systems.
TLDR
Age and dissemination scores from the UFGSI can be used to predict patient outcome and, based on the findings described in this study, patients with a U FGSI score greater than 10 have a higher mortality rate.
Case series of Fournier's gangrene: Affected body surface area – The underestimated prognostic factor
TLDR
Affected BSA is a useful prognostic factor in Fournier's gangrene and the existing prognostic scores can be improved with the introduction of this factor.
Predicting Mortality in Fournier Gangrene and Validating the Fournier Gangrene Severity Index: Our Experience with 50 Patients in a Tertiary Care Center in India
TLDR
Increasing age, diabetes, alcoholic liver disease, bed-ridden status, delayed hospital presentation, and an altered international normalized ratio at presentation are associated with higher mortality in patients with Fournier's Gangrene.
Usefulness of FGSI and UFGSI scoring systems for predicting mortality in patients with Fournier's gangrene: A multicenter study.
TLDR
The FGSI and UFGSI scoring systems are valuable for predicting mortality in patients with FG and the extent of the disease was an important prognostic parameter in this study.
MICROBIOLOGICAL PROFILE, ANTIBIOTIC SENSITIVITY AND PROGNOSIS OF PATIENTS WITH FOURNIER’S GANGRENE: A PROSPECTIVE, HOSPITAL BASED STUDY FROM NORTH INDIA
Background: Fournier's gangrene (FG) is a devastating disease that is characterized by necrotizing fasciitis of the perineal, genital, or perianal region. Broad-spectrum antibiotics are the key
Fournier's Gangrene: From Diagnosis to Reconstruction
TLDR
Although originally thought to be an idiopathic process, FG has been shown to have a predilection for patients with diabetes as well as long-term alcohol misuse; however, it can also affect patients with non‐obvious immune compromise.
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References

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Factors affecting mortality in Fournier's gangrene: experience with fifty-two patients.
TLDR
Haemodialysis-dependent chronic renal failure and a high leukocyte count at first presentation were found to be the factors affecting mortality in FG patients.
Fournier’s gangrene: our experience with 50 patients and analysis of factors affecting mortality
TLDR
The medical records of 50 patients with Fournier’s gangrene who presented at the University Hospital Hassan II of Fez from January 2003 to December 2009 were reviewed retrospectively to analyze the outcome and identify the risk factors and prognostic indicators of mortality.
Fournier’s Gangrene: Risk Factors and Strategies for Management
TLDR
Despite the use of contemporary effective antibiotic treatment, aggressive debridements, and state-of-the-art intensive care conditions, Fournier’s gangrene still has high mortality and morbidity rates.
Predisposing Factors and Treatment Outcome in Fournier’s Gangrene
TLDR
Early recognition of the pathology and aggressive surgical debridement are the mainstay of the management of Fournier’s gangrene and additional strategies to improve wound healing and increase patient survival are also needed.
Epidemiological Characteristics of Fournier’s Gangrene: A Report of 71 Patients
TLDR
The most essential intervention for stopping the rapidly progressing infectious process of FG consists of early recognition of the disease, proper management of the predisposing factors and aggressive surgical debridement.
Prognostic factors in Fournier gangrene.
Fournier's gangrene: overview of prognostic factors and definition of new prognostic parameter.
TLDR
Individual laboratory parameters such as hypomagnesemia, hemoglobin, hematocrit, alkaline phosphatase, creatinine, and the heart and respiratory rates were associated with a better prognosis and low magnesium levels might be a new parameter for a worse prognosis.
The clinical features of Fournier’s gangrene and the predictivity of the Fournier’s Gangrene Severity Index on the outcomes
TLDR
A patient’s metabolic status and the extent of disease at presentation are the most important factors determining the prognosis of FG, and the FGSI score may be considered as an objective and simple tool to predict the outcome in the patient with FG.
Fournier's gangrene: management and mortality predictors in a population based study.
TLDR
Hospitals where more patients with Fournier's gangrene were treated had lower mortality rates, supporting the rationale for regionalized care for this rare disease.
Fournier's gangrene: a review of 110 cases for aetiology, predisposing conditions, microorganisms, and modalities for coverage of necrosed scrotum with bare testes.
TLDR
Review of the cases suggests that the Fournier's gangrene is either an idiopathic condition or secondary to adjacent infection or the operation performed, although it demands surgeons with considerable skill and experience and there are relatively more complications compared with other procedures as well as a longer hospital stay.
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