Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene.

@article{Danielson1994FourSD,
  title={Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene.},
  author={Patria E. Danielson and S Forss-Petter and Elmar Battenberg and L deLecea and Floyd E. Bloom and J. Gregor Sutcliffe},
  journal={Journal of neuroscience research},
  year={1994},
  volume={38 4},
  pages={468-78}
}
Four structurally related neuron-specific 1B426b mRNAs, designated AMY, BMY, AMZ, and BMZ, have been isolated from rat brain cDNA libraries. The four mRNAs are related to one another by their shared M region and by two pairs of alternative 5' (A, B) or 3' (Y, Z) regions. All four possible combinations were detected. The four transcripts are derived by differential promoter utilization (to generate A or B 5' ends) and alternative splicing (to generate Y or Z 3' ends) of the primary transcripts… CONTINUE READING