Four-stranded DNA structures can be stabilized by two different types of minor groove G:C:G:C tetrads.

@article{Escaja2007FourstrandedDS,
  title={Four-stranded DNA structures can be stabilized by two different types of minor groove G:C:G:C tetrads.},
  author={N Escaja and Irene G{\'o}mez-Pinto and Enrique Pedroso and Carlos Gonz{\'a}lez},
  journal={Journal of the American Chemical Society},
  year={2007},
  volume={129 7},
  pages={2004-14}
}
Four-stranded nucleic acid structures are central to many processes in biology and in supramolecular chemistry. It has been shown recently that four-stranded DNA structures are not only limited to the classical guanine quadruplex but also can be formed by tetrads resulting from the association of Watson-Crick base pairs. Such an association may occur through the minor or the major groove side of the base pairs. Structures stabilized by minor groove tetrads present distinctive features, clearly… CONTINUE READING

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