Four signalling domains in the hybrid histidine protein kinase RodK of Myxococcus xanthus are required for activity.

@article{Rasmussen2006FourSD,
  title={Four signalling domains in the hybrid histidine protein kinase RodK of Myxococcus xanthus are required for activity.},
  author={Anders Aa Rasmussen and Sigrun Wegener-Feldbr{\"u}gge and Steven L. Porter and Judith P. Armitage and Lotte S{\o}gaard-Andersen},
  journal={Molecular microbiology},
  year={2006},
  volume={60 2},
  pages={
          525-34
        }
}
In prokaryotes, the principal signal transduction systems operating at the level of protein phosphorylation are the two-component systems. A number of hybrid histidine protein kinases in these systems contain several receiver domains, however, the function of these receiver domains is unknown. The RodK kinase in Myxococcus xanthus has an unconventional domain composition with a putative N-terminal sensor domain followed by a histidine kinase domain and three receiver domains. RodK is essential… CONTINUE READING
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