Four novel sequences in Drosophila melanogaster homologous to the auxiliary Para sodium channel subunit TipE.

@article{Derst2006FourNS,
  title={Four novel sequences in Drosophila melanogaster homologous to the auxiliary Para sodium channel subunit TipE.},
  author={Christian Derst and Christian Walther and R{\"u}diger W Veh and Dieter Wicher and Stefan H. Heinemann},
  journal={Biochemical and biophysical research communications},
  year={2006},
  volume={339 3},
  pages={939-48}
}
TipE is an auxiliary subunit of the Drosophila Para sodium channel. Here we describe four sequences, TEH1-4, homologous to TipE in the Drosophila melanogaster genome, harboring all typical structures of both TipE and the beta-Subunit family of big-conductance Ca(2+)-activated potassium channels: short cytosolic N- and C-terminal stretches, two transmembrane domains, and a large extracellular loop with two disulfide bonds. Whereas TEH1 and TEH2 lack the TipE-specific extension in the… CONTINUE READING

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