Four-dimensional analysis of human brain tumor spheroid invasion into fetal rat brain aggregates using confocal scanning laser microscopy

@article{Khoshyomn1998FourdimensionalAO,
  title={Four-dimensional analysis of human brain tumor spheroid invasion into fetal rat brain aggregates using confocal scanning laser microscopy},
  author={Sami Khoshyomn and Paul L. Penar and Whitney J. McBride and Douglas J Taatjes},
  journal={Journal of Neuro-Oncology},
  year={1998},
  volume={38},
  pages={1-10}
}
The advent of confocal microscopy and fluorescence probes has made possible the routine visualization of the complex three-dimensional structures of thick fixed or live specimens. Four-dimensional (4-D) imaging of biological specimens (three-dimensional image reconstruction of the same living sample at different time points), remains a seldom-used… CONTINUE READING