Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma

@inproceedings{Andresen2015FourDM,
  title={Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma},
  author={Kim Andresen and Kirsten Muri Boberg and Hege Marie Vedeld and Hilde Honne and Peter Jebsen and Merete Hektoen and Christopher A. Wadsworth and O. Clausen and Knut E. A. Lundin and Vemund Paulsen and Aksel Foss and \Oystein Mathisen and Lars Aabakken and Erik Schrumpf and Ragnhild A. Lothe and Guro E Lind},
  booktitle={Hepatology},
  year={2015}
}
UNLABELLED Early detection of the highly aggressive malignancy cholangiocarcinoma (CCA) remains a challenge but has the potential to render the tumor curable by surgical removal. This study evaluates a biomarker panel for the diagnosis of CCA by DNA methylation analyses of biliary brush samples. The methylation status of 13 candidate genes (CDO1, CNRIP1, DCLK1, FBN1, INA, MAL, SEPT9, SFRP1, SNCA, SPG20, TMEFF2, VIM, and ZSCAN18) was investigated in 93 tissue samples (39 CCAs and 54 nonmalignant… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 30 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis.

Toxicology and applied pharmacology • 2017
View 4 Excerpts
Highly Influenced

A novel prognostic biomarker for cholangiocarcinoma: circRNA Cdr1as.

X Jiang, Z Li, +4 authors D-J Sun
European review for medical and pharmacological sciences • 2018

The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma.

Biochimica et biophysica acta. Molecular basis of disease • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Aberrant vimentin methylation is characteristic of upper gastrointestinal pathologies.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2012

Cholangiocarcinoma: epidemiology and risk factors

MC Bragazzi, V Cardinale, +3 authors R Gentile
Transl Gastrointest Cancer 2012;1:21-32 • 2012

Vimentin in upper gastrointestinal pathologies--letter.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…