Foundation for the NIMH strategic plan for mood disorders research

  title={Foundation for the NIMH strategic plan for mood disorders research},
  author={Dennis S. Charney and Kathleen Simko Babich},
  journal={Biological Psychiatry},

Behavioral and emotional dysregulation trajectories marked by prefrontal–amygdala function in symptomatic youth

Patterns of function in lateral prefrontal cortical–amygdala circuitry in youth denote the severity of the developmental trajectory of behavioral and emotional dysregulation over time, and may be biological targets to guide differential treatment and novel treatment development for different levels of Behavioral and emotional Dysregulation in youth.

The use of clinical trials in comparative effectiveness research on mental health.

Bipolar disorder in children: assessment in general pediatric practice

If given the right information and tools, pediatricians are uniquely positioned to interrupt the decline caused by mental illnesses.

Differential patterns of abnormal activity and connectivity in the amygdala-prefrontal circuitry in bipolar-I and bipolar-NOS youth.

Can Basic Risk Research Help in the Prevention of Childhood and Adolescent Depression? Examining a Cognitive and Emotional Regulation Approach

This paper selectively review basic research evidence from community, clinical, and high-risk populations that identifies cognitive mechanisms and emotional regulation as key processes involved in the onset and maintenance of depression.

Methodological issues in molecular genetic studies of mental disorders.

The methodologies employed for genetic investigation of mental disorders, including phenotyping strategies, approaches to genetic mapping, and use of animal models of psychopathology are discussed.

Neural phenotypes of common and rare genetic variants

Melancholia: The Diagnosis, Pathophysiology and Treatment of Depressive Illness

List of patient vignettes Acknowledgements Preface 1. Melancholia: a conceptual history 2. Melancholia defined 3. Defining melancholia by psychopathology 4. Defining melancholia: laboratory tests 5.