Found in translation: high-throughput chemical screening in Arabidopsis thaliana identifies small molecules that reduce Fusarium head blight disease in wheat.

@article{Schreiber2011FoundIT,
  title={Found in translation: high-throughput chemical screening in Arabidopsis thaliana identifies small molecules that reduce Fusarium head blight disease in wheat.},
  author={Karl J Schreiber and Charles G. Nasmith and Ghislaine C Allard and Jasbir K S B Singh and Rajagopal Subramaniam and Darrell Desveaux},
  journal={Molecular plant-microbe interactions : MPMI},
  year={2011},
  volume={24 6},
  pages={640-8}
}
Despite the tremendous economic impact of cereal crop pathogens such as the fungus Fusarium graminearum, the development of strategies for enhanced crop protection is hampered by complex host genetics and difficulties in performing high-throughput analyses. To bypass these challenges, we have developed an assay in which the interaction between F. graminearum and the model plant Arabidopsis thaliana is monitored in liquid media in 96-well plates. In this assay, fungal infection is associated… CONTINUE READING