Fosfomycin-daptomycin and other fosfomycin combinations as alternative therapies in experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.

@article{Garrigs2013FosfomycindaptomycinAO,
  title={Fosfomycin-daptomycin and other fosfomycin combinations as alternative therapies in experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.},
  author={Carmen Garrig{\'o}s and O Sim{\'o}n Murillo and Jaime Lora-Tamayo and Ricard Verdaguer and F{\'e} Tubau and Carmen Cabellos and Javier Cabo and Javier Ariza},
  journal={Antimicrobial agents and chemotherapy},
  year={2013},
  volume={57 1},
  pages={606-10}
}
The efficacy of daptomycin, imipenem, or rifampin with fosfomycin was evaluated and compared with that of daptomycin-rifampin in a tissue cage model infection caused by methicillin-resistant Staphylococcus aureus (MRSA). Strain HUSA 304 was used. The study yielded the following results for MICs (in μg/ml): fosfomycin, 4; daptomycin, 1; imipenem, 0.25; and rifampin, 0.03. The study yielded the following results for minimum bactericidal concentration (MBC) (in μg/ml): fosfomycin, 8; daptomycin, 4… CONTINUE READING
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High efficacy of fosfomycin-rifampin combination against methicillin-resistant Staphylococcus aureus in an experimental model of foreign-body infection, abstr P-2062

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