Fos immunocytochemical studies on the neuroanatomical sites of action of acute tyrosine depletion in the rat brain

@article{Masurier2004FosIS,
  title={Fos immunocytochemical studies on the neuroanatomical sites of action of acute tyrosine depletion in the rat brain},
  author={Marisa Le Masurier and Philip J. Cowen and Trevor Sharp},
  journal={Psychopharmacology},
  year={2004},
  volume={171},
  pages={435-440}
}
Acute depletion of brain tyrosine using a tyrosine-free amino acid mixture offers a nutritional approach to reduce central catecholamine function. Recent preclinical data suggest that tyrosine-free amino acid mixtures may have region-specific effects through targeting dopamine neurones. Here we used fos immunocytochemistry to examine the neuroanatomical sites of action of a tyrosine-free amino acid mixture administered either alone or combined with amphetamine. Rats (male, Sprague Dawley, 240… CONTINUE READING