Forward and reverse genetic approaches to the analysis of eye development in zebrafish

@article{Malicki2002ForwardAR,
  title={Forward and reverse genetic approaches to the analysis of eye development in zebrafish},
  author={Jarema J Malicki and Zac Pujic and Christine I Thisse and Bernard V Thisse and Xiangyun Wei},
  journal={Vision Research},
  year={2002},
  volume={42},
  pages={527-533}
}
The zebrafish has been established as a mainstream research system, largely due to the immense success of genetic screens. Over 2000 mutant alleles affecting zebrafish's early development have been isolated in two large-scale morphological screens and several smaller efforts. So far, over 50 mutant strains display retinal defects and many more have been shown to affect the retinotectal projection. More recently, mutant isolation and characterization have been successfully followed by candidate… CONTINUE READING

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