Forskolin and antidiuretic hormone stimulate a Ca2+-activated K+ channel in cultured kidney cells.


Single channels in the apical cell membrane of primary cultured chick kidney cells were studied using the patch clamp technique. Cell-attached recordings revealed the presence of a 107 +/- 6 pS channel that increased fractional open time upon depolarization. Experiments with inside-out excised patches indicated that the channel is K+ selective, Ca2… (More)


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