• Biology, Medicine
  • Published in Journal of immunology 1987

Formyl peptide leukocyte chemoattractant uptake and release by cultured human umbilical vein endothelial cells.

@article{Rotrosen1987FormylPL,
  title={Formyl peptide leukocyte chemoattractant uptake and release by cultured human umbilical vein endothelial cells.},
  author={Daniel Rotrosen and Harry L Malech and John I Gallin},
  journal={Journal of immunology},
  year={1987},
  volume={139 9},
  pages={
          3034-40
        }
}
Recent observations support an active role for the vascular endothelial cell in the induction and evolution of the inflammatory response. Since prior studies suggested that cultured bovine endothelial cells express high affinity binding sites for the neutrophil chemotactic oligopeptide formyl methionyl-leucyl-phenylalanine (f-Met-Leu-Phe), we sought to further characterize the interaction between formyl peptide chemoattractants and human vascular endothelial cells. Cultured human umbilical vein… CONTINUE READING

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