Formyl peptide chemotaxis receptors on the rat neutrophil: experimental evidence for negative cooperativity.

Abstract

To examine the existence of negative cooperativity among formyl peptide chemotaxis receptors, steady-state binding of f Met-Leu-[3H]Phe to viable rat neutrophils and their purified plasma membranes was measured and the data were subjected to statistical analysis and to computer curve fitting using the NONLIN computer program. Curvilinear, concave upward… (More)

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