Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition.

@article{Ubale2013FormulationOM,
  title={Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition.},
  author={Ruhi V. Ubale and Martin J D'souza and Daniel T. Infield and Nael A. McCarty and Susu M Zughaier},
  journal={Journal of microencapsulation},
  year={2013},
  volume={30 1},
  pages={28-41}
}
Neisseria meningitidis is a leading cause of bacterial meningitis and sepsis associated with a high mortality rate. Capsular polysaccharides (CPSs) are a major virulence factor and form the basis for serogroup designation and protective vaccines. The current polysaccharide meningococcal vaccines are available but are very expensive and require chemical conjugation. Here, we report a novel meningococcal vaccine formulation consisting of meningococcal CPS polymers encapsulated in albumin-based… CONTINUE READING

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Albumin receptors-structure and function, in cellular proteins and their fatty acids in health and disease

  • NJ Brunskill
  • KGaA: Weinheim, FRG: Wiley-VCH Verlag GmbH & Co
  • 2004
Highly Influential
4 Excerpts

Image processing with image

  • MD Abramoff, PJ Magelhaes, SJ. Ram
  • J Biophoton Int,
  • 2004
Highly Influential
3 Excerpts

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