Formulation of Sodium Alginate Nanospheres Containing Amphotericin B for the Treatment of Systemic Candidiasis

@inproceedings{Sangeetha2007FormulationOS,
  title={Formulation of Sodium Alginate Nanospheres Containing Amphotericin B for the Treatment of Systemic Candidiasis},
  author={Shanmugasundaram Sangeetha and Dhandapani Nagasamy Venkatesh and Rajendran Adhiyaman and Kumaraswamy Santhi and Bhojraj Suresh},
  year={2007}
}
Purpose: The aim of this work was to formulate sodium alginate nanospheres of amphotericin B by controlled gellification method and to evaluate the role of the nanospheres as a “passive carrier” in targeted antifungal therapy. Methods: Sodium alginate nanospheres of amphotericin B were prepared by controlled gellification method, and the particle size analysis was carried out by scanning electron microscopy. The carrier capacity of sodium alginate was evaluated in terms of drug to polymer ratio… CONTINUE READING

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