Formulation design of carbamazepine fast-release tablets prepared by melt granulation technique.

@article{Perissutti2003FormulationDO,
  title={Formulation design of carbamazepine fast-release tablets prepared by melt granulation technique.},
  author={Beatrice Perissutti and Fulvio Rubessa and Mariarosa Moneghini and Dario Voinovich},
  journal={International journal of pharmaceutics},
  year={2003},
  volume={256 1-2},
  pages={53-63}
}
This work describes a new approach to prepare a fast-release dosage form for carbamazepine (CBZ), involving the use of melt granulation process in high shear mixer for the production of tablets. In particular, the granules containing CBZ were prepared using polyethylene glycol (PEG) 4000 as a melting binder and lactose monohydrate as a hydrophilic filler… CONTINUE READING