Formulation and evaluation of matrix microspheres for simultaneous delivery of salbutamol sulphate and theophylline

@inproceedings{Pachuau2008FormulationAE,
  title={Formulation and evaluation of matrix microspheres for simultaneous delivery of salbutamol sulphate and theophylline},
  author={Lalduh Sanga Pachuau and Sourav Sarkar and Bhaskar Mazumder},
  year={2008}
}
Purpose: The objective of this study was to formulate and evaluate a matrix microsphere system for simultaneous delivery of two anti-asthmatic drugs Salbutamol sulphate and Theophylline which are often indicated for the management of asthma, their frequent dosing may reduce compliance, thus making a prolonged release formulation necessary. Ethylcellulose was used as a retardant polymer and its compatibility with the drugs and the drug-drug compatibility were established through IR, XRD and DSC… CONTINUE READING

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