Formulation and evaluation of clotrimazole transdermal spray.

  title={Formulation and evaluation of clotrimazole transdermal spray.},
  author={Mansi Paradkar and Vaishali Tejas Thakkar and Tejal G. Soni and Tejal Gandhi and Mukesh C. Gohel},
  journal={Drug development and industrial pharmacy},
  volume={41 10},
CONTEXT Transdermal spray (TS) of clotrimazole (CTZ) was formulated to improve the drug transport through the skin up to 12 h to achieve the antifungal efficacy. OBJECTIVE The aim of present study was to formulate and evaluate antifungal transdermal spray to improve the permeation of clotrimazole across the skin and to decrease the dosing frequency in fungal infection. MATERIALS AND METHODS Different ratios of ethanol and acetone and various grades of eudragit and ethyl cellulose were… CONTINUE READING
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