Formulation and evaluation of Nanostructured Lipid Carrier (NLC)-based gel of Valdecoxib.

@article{Joshi2006FormulationAE,
  title={Formulation and evaluation of Nanostructured Lipid Carrier (NLC)-based gel of Valdecoxib.},
  author={Medha D Joshi and Vandana Bhalla Patravale},
  journal={Drug development and industrial pharmacy},
  year={2006},
  volume={32 8},
  pages={911-8}
}
Nanostructured Lipid Carrier (NLC)-based topical gel of Valdecoxib was formulated with the aim of faster onset yet prolonged action for the treatment of inflammation and allied conditions. NLCs prepared by microemulsion template technique were characterized by photon correlation spectroscopy for size. Drug encapsulation efficiency was determined using Nanosep centrifugal device. The nanoparticulate dispersion was suitably gelled and characterized with respect to drug content, pH, spreadibility… CONTINUE READING