Formulation and Development of Colon Specific Multiparticulate System of Capecitabine

  title={Formulation and Development of Colon Specific Multiparticulate System of Capecitabine},
  author={Nandgude Tanaji Dilip},
  journal={Asian Journal of Pharmaceutics},
  • N. Dilip
  • Published 10 September 2016
  • Biology
  • Asian Journal of Pharmaceutics
Aim: In the present study, the main objective was to develop a multiparticulate system containing chitosan microspheres for colon-specific drug delivery of capecitabine for the treatment of colorectal cancer. Materials and Methods: This study was based on the microbial degradability of chitosan microspheres. The microspheres were prepared with chitosan by emulsion cross linking method. A factorial design was applied to optimize the formulation. The effect of concentration of chitosan and drug… 

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