Formulation Design and Optimization of Novel Taste Masked Mouth-Dissolving Tablets of Tramadol Having Adequate Mechanical Strength

@article{Madgulkar2009FormulationDA,
  title={Formulation Design and Optimization of Novel Taste Masked Mouth-Dissolving Tablets of Tramadol Having Adequate Mechanical Strength},
  author={Ashwini R. Madgulkar and Mangesh Ramesh Bhalekar and Rahul R. Padalkar},
  journal={AAPS PharmSciTech},
  year={2009},
  volume={10},
  pages={574-581}
}
The purpose of this work was to develop novel taste masked mouth-dissolving tablets of tramadol that overcomes principle drawback of such formulation which is inadequate mechanical strength. Tramadol is an opioid analgesic used for the treatment of moderate to severe pain. Mouth-dissolving tablets offer substantial advantages like rapid onset of action, beneficial for patients having difficulties in swallowing and in conditions where access to water is difficult. The crucial aspect in the… CONTINUE READING
17 Citations
22 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Formulation and in vitro evaluation of taste masked orodispersible dosage form of Levocetirizine dihydrochloride

  • P Chaudhari, S Chaudhari, S Lanke, N. Patel
  • Indian J Pharm Edu Res
  • 2007

Fast dissolving drug delivery system: a brief overview

  • S Biradar, S Bhagavati, Kuppasad
  • Internet J Pharmacol
  • 2006

Manufacturing technologies for mouth dissolving tablets

  • U Bagul
  • www.pharmainfo.net,
  • 2006

Fast dissolving tablets. US Pharmacist 2005;27:03

  • R Bogner, F. Meghan
  • 2005

A new method for disintegration studies of rapid disintegrating tablets

  • R Narazki, T Harada, N Takami, Y Koto, T. Ohwaki
  • Chem Pharm Bull ( Tokyo )
  • 2004

A novel method for predicting disintegration time in the mouth of rapid disintegrating tablet by compaction analysis using Tab All

  • Y Watanabe, Y Yamamoti, M Fujii, M Kondoh, Y. Shibata
  • Chem Pharm Bull ( Tokyo )
  • 2004

Cation exchange resins for taste masking and rapid dissolution of sparfloxacin

  • J Avari, M. Bhalekar
  • Indian Drugs
  • 2004

Clinical pharmacology of tramadol

  • S Grond, A. Sablotzi
  • Clin Pharmacokinet
  • 2004

Similar Papers

Loading similar papers…