Formoterol on airway smooth muscle and human lung mast cells: a comparison with salbutamol and salmeterol.

@article{Nials1994FormoterolOA,
  title={Formoterol on airway smooth muscle and human lung mast cells: a comparison with salbutamol and salmeterol.},
  author={Anthony T. Nials and D. I. Ball and Peter R Butchers and Robert A. Coleman and Alison A. Humbles and Malcolm Johnson and C. J. Vardey},
  journal={European journal of pharmacology},
  year={1994},
  volume={251 2-3},
  pages={
          127-35
        }
}
Formoterol, like salbutamol and salmeterol, relaxed isolated preparations of guinea-pig trachea and human bronchus, and inhibited antigen-induced mediator release from human lung fragments in a concentration-related fashion. In each case, these actions were mediated through beta 2-adrenoceptors, with formoterol being 50-120-fold more potent than salbutamol, and 2-27-fold more potent than salmeterol. The duration of action of formoterol was longer than that of salbutamol in all preparations, but… CONTINUE READING
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