Formation of toxic iodinated disinfection by-products from compounds used in medical imaging.

  title={Formation of toxic iodinated disinfection by-products from compounds used in medical imaging.},
  author={Stephen E. Duirk and Cristal Lindell and Christopher C. Cornelison and Jennifer Lynne Kormos and Thomas A. Ternes and Matias Attene-Ramos and Jennifer Osiol and Elizabeth D. Wagner and Michael J. Plewa and Susan D. Richardson},
  journal={Environmental science \& technology},
  volume={45 16},
Iodinated X-ray contrast media (ICM) were investigated as a source of iodine in the formation of iodo-trihalomethane (iodo-THM) and iodo-acid disinfection byproducts (DBPs), both of which are highly genotoxic and/or cytotoxic in mammalian cells. ICM are widely used at medical centers to enable imaging of soft tissues (e.g., organs, veins, blood vessels) and are designed to be inert substances, with 95% eliminated in urine and feces unmetabolized within 24 h. ICM are not well removed in… 

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