Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone.

@article{Winter2009FormationOT,
  title={Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone.},
  author={Jaclyn M. Winter and Ariane L Jansma and Tracy M. Handel and Bradley S Moore},
  journal={Angewandte Chemie},
  year={2009},
  volume={48 4},
  pages={767-70}
}
Compounds containing N N bonds have been made synthetically for over a hundred years. However, it wasn t until 1951 that the first naturally occurring compound containing a dinitrogen group, the azoxy-containing toxin macrozamin, was reported. Since that time, natural products containing hydrazine, nitrosamine, azoxy, diazo, and other N N-bonded functional… CONTINUE READING