Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly

@inproceedings{Lu2011FormationOT,
  title={Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly},
  author={Lei Lu and Mark S Ladinsky and Tomas Kirchhausen},
  booktitle={The Journal of cell biology},
  year={2011}
}
During mitosis, the nuclear envelope merges with the endoplasmic reticulum (ER), and nuclear pore complexes are disassembled. In a current model for reassembly after mitosis, the nuclear envelope forms by a reshaping of ER tubules. For the assembly of pores, two major models have been proposed. In the insertion model, nuclear pore complexes are embedded in the nuclear envelope after their formation. In the prepore model, nucleoporins assemble on the chromatin as an intermediate nuclear pore… CONTINUE READING
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