Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions.

@article{Garrett2010FormationOP,
  title={Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions.},
  author={Mark P Garrett and Udaya Kumar Kakarla and Randall W. Porter and Volker K. H. Sonntag},
  journal={Neurosurgery},
  year={2010},
  volume={66 6},
  pages={1044-9; discussion 1049}
}
BACKGROUND The use of bone morphogenetic proteins for fusion augmentation in spine surgery has increased dramatically in recent years. Information is continually emerging regarding the effectiveness and safety profile of these compounds. OBJECTIVE We have noted an increased incidence in sterile seroma formation and painful edema after the use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for posterolateral lumbar fusion. We present a retrospective review to determine the… CONTINUE READING

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