Formation of nucleophosmin/B23 oligomers requires both the amino- and the carboxyl-terminal domains of the protein.

@article{Liu1991FormationON,
  title={Formation of nucleophosmin/B23 oligomers requires both the amino- and the carboxyl-terminal domains of the protein.},
  author={Qiong Liu and Pick Kuen Chan},
  journal={European journal of biochemistry},
  year={1991},
  volume={200 3},
  pages={715-21}
}
Nucleophosmin/B23 is a nucleolar phosphoprotein which forms oligomers. To determine the domain essential for oligomer formation, various deletion and point mutation clones of nucleophosmin/B23 were constructed. Nucleophosmin/B23 and the mutant proteins were produced by (a) coupled in vitro transcription and translation and (b) expression in Escherichia coli… CONTINUE READING