Formation of membrane-defined compartments by tick-borne encephalitis virus contributes to the early delay in interferon signaling.

@article{Miorin2012FormationOM,
  title={Formation of membrane-defined compartments by tick-borne encephalitis virus contributes to the early delay in interferon signaling.},
  author={Lisa Miorin and Amelina Albornoz and Marycelin Mandu Baba and Pierlanfranco D’Agaro and Alessandro Marcello},
  journal={Virus research},
  year={2012},
  volume={163 2},
  pages={
          660-6
        }
}
Interferons are key mediators of the innate antiviral response of the cell against viral infections. Viruses on the other hand have evolved various strategies to delay innate immunity in order to establish a productive infection. In this work we analyzed the pathway of interferon induction by the tick-borne encephalitis virus. We initially observed a consistent delay of interferon induction following virus replication. RIG-I, but not MDA5, and nuclear translocation of IRF3 were eventually… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function

A. ula, J. Guerra, +3 authors A. Marcello
  • Retrovirology
  • 2011

Toll - like receptors and their crosstalk with other innate receptors in infection and

T. awai, S. Akira
  • immunity
  • 2011

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

T. awai, S. Akira
  • Immunity
  • 2011