Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits

@article{Joiner1998FormationOI,
  title={Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits},
  author={William J. Joiner and Michael D. Tang and L Y Wang and Steven I. Dworetzky and Christopher G. Boissard and Li Gan and Valentin K. Gribkoff and Leonard K Kaczmarek},
  journal={Nature Neuroscience},
  year={1998},
  volume={1},
  pages={462-469}
}
Large-conductance calcium-activated potassium channels (maxi-K channels) have an essential role in the control of excitability and secretion. Only one gene Slo is known to encode maxi-K channels, which are sensitive to both membrane potential and intracellular calcium. We have isolated a potassium channel gene called Slack that is abundantly expressed in the nervous system. Slack channels rectify outwardly with a unitary conductance of about 25–65 pS and are inhibited by intracellular calcium… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 62 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Similar Papers

Loading similar papers…