Formation of cigarette smoke-induced DNA adducts in the rat lung and nasal mucosa.

Abstract

The formation of DNA adducts in the nasal, lung, and liver tissues of rats exposed daily to fresh smoke from a University of Kentucky reference cigarette (2R1) for up to 40 weeks was examined. The amount of smoke total particulate matter (TPM) inhaled and the blood carboxyhemoglobin (COHb) values averaged 5-5.5 mg smoke TPM/day/rat and 5.5%, respectively… (More)

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@article{Gupta1989FormationOC, title={Formation of cigarette smoke-induced DNA adducts in the rat lung and nasal mucosa.}, author={R. C. Gupta and Mohan L. Sopori and C. G. Gairola}, journal={Cancer research}, year={1989}, volume={49 8}, pages={1916-20} }