Formation of chlorocatechol meta cleavage products by a pseudomonad during metabolism of monochlorobiphenyls.

@article{Arensdorf1994FormationOC,
  title={Formation of chlorocatechol meta cleavage products by a pseudomonad during metabolism of monochlorobiphenyls.},
  author={Joseph J. Arensdorf and Dennis D. Focht},
  journal={Applied and environmental microbiology},
  year={1994},
  volume={60 8},
  pages={2884-9}
}
Pseudomonas cepacia P166 was able to metabolize all monochlorobiphenyls to the respective chlorobenzoates. Although they transiently accumulated, the chlorobenzoate degradation intermediates were further metabolized to chlorocatechols, which in turn were meta cleaved. 2- and 3-Chlorobiphenyl both produced 3-chlorocatechol, which was transformed to an acyl halide upon meta cleavage. 3-Chlorocatechol metabolism was toxic to the cells and impeded monochlorobiphenyl metabolism. In the case of 2… CONTINUE READING
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