Formation of bone-like mineralized matrix by periodontal ligament cells in vivo: a morphological study in rats

@article{Hiraga2009FormationOB,
  title={Formation of bone-like mineralized matrix by periodontal ligament cells in vivo: a morphological study in rats},
  author={Toru Hiraga and Tadashi Ninomiya and Akihiro Hosoya and Masafumi Takahashi and Hiroaki Nakamura},
  journal={Journal of Bone and Mineral Metabolism},
  year={2009},
  volume={27},
  pages={149-157}
}
Periodontal ligament (PDL) is a unique connective tissue that not only connects cementum and alveolar bone to support teeth, but also plays an important role in reconstructing periodontal tissues. Previous studies have suggested that PDL cells have osteogenic potential; however, they lack precise histological examinations. Here, we studied bone-like matrix formation by PDL cells in rats using morphological techniques. Rat and human PDL cells exhibited substantial alkaline phosphatase activity… CONTINUE READING

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