Formation of adducts of parthenin and related sesquiterpene lactones with cysteine and glutathione.

Abstract

Parthenin, the major sesquiterpene lactone of Parthenium hysterophorus, a weed responsible for dermatitis in man is primarily restricted to leaf and stem trichomes. Parthenin forms a monoadduct with L-cysteine through the alpha-methylene group of the gamma-lactone and a biadduct with the endocyclic double bond on the cyclopentenone ring. Studies with other… (More)

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Cite this paper

@article{Picman1979FormationOA, title={Formation of adducts of parthenin and related sesquiterpene lactones with cysteine and glutathione.}, author={A K Picman and Edgardo R. Rodriguez and G. H. Neil Towers}, journal={Chemico-biological interactions}, year={1979}, volume={28 1}, pages={83-9} }