Formation of F-ring isoprostane-like compounds (F3-isoprostanes) in vivo from eicosapentaenoic acid.

@article{Gao2006FormationOF,
  title={Formation of F-ring isoprostane-like compounds (F3-isoprostanes) in vivo from eicosapentaenoic acid.},
  author={Ling Gao and Huiyong Yin and Ginger L Milne and Ned A. Porter and Jason D. Morrow},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 20},
  pages={14092-9}
}
Eicosapentaenoic acid (EPA, C20:5, omega-3) is the most abundant polyunsaturated fatty acid (PUFA) in fish oil. Recent studies suggest that the beneficial effects of fish oil are due, in part, to the generation of various free radical-generated non-enzymatic bioactive oxidation products from omega-3 PUFAs, although the specific molecular species responsible for these effects have not been identified. Our research group has previously reported that pro-inflammatory prostaglandin F2-like… CONTINUE READING

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