Formation of Charcot-Leyden crystals by human basophils

  title={Formation of Charcot-Leyden crystals by human basophils},
  author={S J Ackerman and Gary J Weil and Gerald J. Gleich},
  journal={The Journal of Experimental Medicine},
  pages={1597 - 1609}
Charcot-Leyden crystals (CLC) are currently believed to be unique to the eosinophil and a hallmark of active eosinophilic inflammation or proliferation. The distinctiveness of the CLC to the eosinophil was questioned in 1965 by Archer and Blackwood (9), but their demonstration of CLC formation in basophils was ignored and later dismissed (1) as being the result of eosinophil contamination of basophil-enriched cell suspensions. We reexamined this question and showed that basophils obtained from… CONTINUE READING
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