Corpus ID: 20194950

Formation of 15alpha-hydroxyestriol and 15alpha-hydroxyestradiol from C19 15alpha-hydroxylated precursors in human pregnancy.

@article{Stanczyk1978FormationO1,
  title={Formation of 15alpha-hydroxyestriol and 15alpha-hydroxyestradiol from C19 15alpha-hydroxylated precursors in human pregnancy.},
  author={F. Stanczyk and S. Solomon},
  journal={Steroids},
  year={1978},
  volume={31 5},
  pages={
          627-43
        }
}
  • F. Stanczyk, S. Solomon
  • Published 1978
  • Medicine
  • Steroids
  • A mixture of 3H-15alpha-hydroxyandrostenedione and 14C-15alpha-hydroxydehydroisoandrosterone was injected intravenously into two subjects in the third trimester of pregnancy and, in a second study, directly into two fetuses in utero during transfusion for erythroblastosis fetalis. The urine was collected for 4-5 days and steroid conjugates in the urine were hydrolyzed into sulfate and glucosiduronate fractions. From the glucosiduronate fraction 15alpha-hydroxyestriol, 15alpha-hydroxyestradiol… CONTINUE READING

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