Formation and toxicity of anesthetic degradation products.

  • María Anders
  • Published 2005 in Annual review of pharmacology and toxicology


Toxic degradation products are formed from a range of old and modern anesthetic agents. The common element in the formation of degradation products is the reaction of the anesthetic agent with the bases in the carbon dioxide absorbents in the anesthesia circuit. This reaction results in the conversion of trichloroethylene to dichloroacetylene, halothane to… (More)