Formation and study of single metal ion-phospholipid complexes in biphasic electrospray ionization mass spectrometry.

@article{Prudent2010FormationAS,
  title={Formation and study of single metal ion-phospholipid complexes in biphasic electrospray ionization mass spectrometry.},
  author={M Prudent and Manuel Alejandro M{\'e}ndez and Daniel F Jana and Cl{\'e}mence Corminboeuf and Hubert H Girault},
  journal={Metallomics : integrated biometal science},
  year={2010},
  volume={2 6},
  pages={400-6}
}
Single metal ion-phospholipid complexes are observed in biphasic electrospray ionization mass spectrometry (BESI-MS) using a dual-channel microsprayer. Such a microsprayer makes it possible to put into contact two immiscible liquids within the Taylor cone. Thus, L-α-dipalmitoyl phosphatidylcholine (DPPC) dissolved in 1,2-dichloroethane (DCE) reacts with aqueous metal cations (M = Na(+), K(+), Ca(2+), Cu(2+), La(3+)) yielding the formation of [M-DPPC(n)](z+) complexes. The number of phospholipid… CONTINUE READING