Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release

Abstract

Dendritic spines are the major transmitter reception compartments of glutamatergic synapses in most principal neurons of the mammalian brain and play a key role in the function of nerve cell circuits. The formation of functional spine synapses is thought to be critically dependent on presynaptic glutamatergic signaling. By analyzing CA1 pyramidal neurons in… (More)
DOI: 10.1016/j.neuron.2017.03.029

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