Formate in serum and urine after controlled methanol exposure at the threshold limit value.

@article{DAlessandro1994FormateIS,
  title={Formate in serum and urine after controlled methanol exposure at the threshold limit value.},
  author={Anthony J. D'Alessandro and John D. Osterloh and P Chuwers and Patty Quinlan and Thomas J. Kelly and Charles E. Becker},
  journal={Environmental Health Perspectives},
  year={1994},
  volume={102},
  pages={178 - 181}
}
Methanol will be present as a new air pollutant when methanol-powered vehicles are introduced in the United States. Little is known about the effect of low-dose methanol exposure. It is controversial whether or not formate, the main metabolite responsible for methanol's acute toxicity, is a sensitive biological marker of toxicity or exposure. We studied the effect of a 4-hr exposure at rest to 200 ppm of methanol vapors on endogenous serum formate and on urinary formic acid excretion. A… CONTINUE READING
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