Formate and its role in hydrogen production in Escherichia coli.

@article{Sawers2005FormateAI,
  title={Formate and its role in hydrogen production in Escherichia coli.},
  author={R. Gary Sawers},
  journal={Biochemical Society transactions},
  year={2005},
  volume={33 Pt 1},
  pages={
          42-6
        }
}
  • R. Sawers
  • Published 1 February 2005
  • Biology, Chemistry
  • Biochemical Society transactions
The production of dihydrogen by Escherichia coli and other members of the Enterobacteriaceae is one of the classic features of mixed-acid fermentation. Synthesis of the multicomponent, membrane-associated FHL (formate hydrogenlyase) enzyme complex, which disproportionates formate into CO(2) and H(2), has an absolute requirement for formate. Formate, therefore, represents a signature molecule in the fermenting E. coli cell and factors that determine formate metabolism control FHL synthesis and… 
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