Formaldehyde in brain: an overlooked player in neurodegeneration?

  title={Formaldehyde in brain: an overlooked player in neurodegeneration?},
  author={Ketki Tulpule and Ralf Dringen},
  journal={Journal of neurochemistry},
  volume={127 1},
Formaldehyde is an environmental pollutant that is also generated in substantial amounts in the human body during normal metabolism. This aldehyde is a well-established neurotoxin that affects memory, learning, and behavior. In addition, in several pathological conditions, including Alzheimer's disease, an increase in the expression of formaldehyde-generating enzymes and elevated levels of formaldehyde in brain have been reported. This article gives an overview on the current knowledge on the… CONTINUE READING
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