Formaldehyde fixation.

@article{Fox1985FormaldehydeF,
  title={Formaldehyde fixation.},
  author={CecilH. Fox and Franklin B. Johnson and James W Whiting and Peter Paul Roller},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1985},
  volume={33 8},
  pages={
          845-53
        }
}
The use of formaldehyde as a biological reagent occurred rather late in the history of histological methodology. The reason for this lay not in any lack of astuteness on the part of pathologists and histologists, but rather with the late development of formaldehyde manufacture by the chemical industry. While formaldehyde was discovered by Butlerov in 1859, practical aspects of the manufacture of this, the simplest aldehyde, only emerged in 1868 when Van Hoffman, as an academic exercise… CONTINUE READING

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